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O4139
Sigma
Orlistat
≥98%, solid
| Synonym: | (−)-Tetrahydrolipstatin, Ro-18-0647, N-Formyl-L-leucine (1S)-1-[[(2S,3S)-3-hexyl-4-oxo-2-oxetanyl]methyl]dodecyl ester |
| CAS Number: | 96829-58-2 |
| Linear Formula: | C29H53NO5 |
| Molecular Weight: | 495.73 |
| MDL number: | MFCD05662360 |
| PubChem Substance ID: | 24724564 |
Description
| Biochem/physiol Actions | Orlistat, used in obesity research, is a pancreatic lipase inhibitor, which acts locally in the gastrointestinal tract to inhibit lipase. |
| Other Notes | Solution is not completely clear, small particles may remain floating. |
Properties
| assay | ≥98% |
| form | solid |
| color | white |
| mp | <50 °C |
| solubility | DMSO: 19 mg/mL |
| Gene Information | human ... PNLIP(5406) |
| storage temp. | 2-8°C |
Safety
| Personal Protective Equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
| WGK Germany | 3 |
| RTECS | OH3167600 |
References
| reference | Lucas, K.H., et al., Orlistat-a novel weight loss therapy. Ann. Pharmacother. 35, 314-328, (2001) |
